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ANTP Class
Families List  Genes List
Msx Family
The Msx or Msh homeobox gene family is named after the Drosophila gene muscle segment homeobox (msh), now renamed Drop. Humans have two Msx family genes, MSX1 and MSX2, generated by genome duplication early in vertebrate evolution. A third Msx gene (Msx3) generated by the same duplication events has been lost in humans, but is present in mice (Shimeld et al. 1996). An additional human Msx sequence, originally thought to be MSX4, is actually a reverse transcribed pseudogene generated from MSX2 (MSX2P1). Comparative genomics indicates that an ancestral Msx gene was originally part of the NK homeobox gene cluster.

Reference(s):
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
Shimeld SM et al. (1996) Mech Dev 55:201-210.
 
Families List of Class ANTP :
HOXL subclass
Cdx(22)Evx(17)Gbx(15)Gsx(13)Hox1(21)Hox2(13)Hox3(25)Hox4(24)Hox5(19)Hox6-8(55)
Hox9-13(15)(96)Meox(14)Mnx(15)Pdx(6)       
NKL subclass
Abox(5)Ankx(1)Barhl(16)Bari(4)Barx(10)Bsx(10)Dbx(15)Dlx(35)Emx(22)En(19)
Hhex(10)Hlx(9)Hx(1)Lbx(14)Lcx(1)Msx(22)Msxlx(3)Nanog(15)Nedx(5)Nk1(17)
Nk2.1(18)Nk2.2(15)Nk3(14)Nk4(19)Nk5/Hmx(25)Nk6(19)Nk7(4)Noto(10)Ro(5)Tlx(19)
Vax(12)Ventx(18)         
 
Loci in Msx of All back to top..
Symbol/LocusNameFamilyOrganismRegulator
msxamuscle segment homeobox AMsxZebrafish 
msxbmuscle segment homeobox BMsxZebrafish 
msxcmuscle segment homeobox CMsxZebrafish 
msxdmuscle segment homeobox DMsxZebrafish 
msxemuscle segment homeobox EMsxZebrafish 
vab-15Variable ABnormal morphology 15MsxNematode 
Msx1 MsxMouse 
Msx2 MsxMouse 
Msx3 MsxMouse 
MSX1msh homeobox 1MsxHuman 
MSX2msh homeobox 2MsxHuman 
MSX2P1msh homeobox 2 pseudogeneMsxHuman 
Dr1Drop1MsxHoneybee 
Dr2Drop2MsxHoneybee 
DrDropMsxFruitfly 
msx1msh homeobox 1MsxFrog 
msx2msh homeobox 2MsxFrog 
MSX1msh homeobox 1MsxChicken 
MSX2msh homeobox 2MsxChicken 
Dr1Drop1MsxBeetle 
Dr2Drop2MsxBeetle 
MsxMsxMsxAmphioxus