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PRD Class
Families List  Genes List
Shox Family
There are two human genes in the Shox gene family: SHOX and SHOX2. The SHOX (short stature homeobox) gene is located in the PAR1 pseudoautosomal region of the X and Y chromosomes; haploinsufficiency of SHOX is implicated in the short stature phenotype of Turner syndrome patients who lack one copy of the X chromosome (Rao et al. 1997). Shox has been lost from mouse, although Shox2 is present (Zhong and Holland 2011). There is one amphioxus orthologue and one Drosophila orthologue (CG34367).

Reference(s):
Rao E et al. (1997) Nat Genet 16:54-63.
Zhong YF, Holland PWH (2011) BMC Evol Biol 11: 169-204.
 
Families List of Class PRD :
Alx(16)AprdA(1)AprdB(1)AprdC(1)AprdD(2)AprdE(1)Argfx(3)Arx(14)CG11294(3)
Dmbx(8)Dprx(8)Drgx(9)Dux(42)Esx(2)Gsc(14)Hbn(3)Hesx(5)Hopx(5)
Isx(5)Leutx(1)Mix(7)Nobox(5)Obox(36)Otp(12)Otx(24)Pax2/5/8(12)Pax3/7(24)
Pax4/6(24)Phox(17)Pitx(20)Prop(8)Prrx(14)Rax(14)Repo(4)Rhox(39)Sebox(3)
Shox(12)Tprx(5)Uncx(16)Vsx(18)      
 
Loci in Shox of All back to top..
Symbol/LocusNameFamilyOrganismRegulator
shoxshort stature homeoboxShoxZebrafish 
shox2short stature homeobox 2ShoxZebrafish 
Shox2 ShoxMouse 
SHOXshort stature homeoboxShoxHuman 
SHOX2short stature homeobox 2ShoxHuman 
ShoxShoxShoxHoneybee 
CG34367CG34367ShoxFruitfly 
shoxshort stature homeobox ShoxFrog 
shox2short stature homeobox 2 ShoxFrog 
SHOX2short stature homeobox 2ShoxChicken 
ShoxShoxShoxBeetle 
ShoxShoxShoxAmphioxus