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PRD Class
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Tprx Family
The Tprx gene family contains one probable functional gene in human, plus one tandem duplicate that is possibly non-functional (TPRX2P)); this sit either side of the Otx-family CRX gene. The dog genome shows the same arrangement (Zhong and Holland 2011). Human also has two clear retrotransposed pseudogenes (TPRX1P1, TPRX1P2) and one unusual, probably non-functional, expressed sequence (TPRXL); Booth and Holland (2007). The TPRX1 locus is incorrectly annotated in the NCBI and EBI assemblies, as EST data indicates an additional 5' exon and different homeobox sequence. Mouse is lacking clear Tprx orthologues although the Crxos1 gene occupies the same location (Zhong and Holland 2011).

Reference(s):
Booth HAF, Holland PWH (2007) Gene 387:7-14.
Zhong YF, Holland PWH (2011) BMC Evol Biol 11: 169-204.
 
Families List of Class PRD :
Alx(3)Argfx(3)Arx(1)Dmbx(1)Dprx(8)Drgx(1)Dux(36)Esx(1)Gsc(2)
Hesx(1)Hopx(1)Isx(1)Leutx(1)Mix(1)Nobox(1)Otp(1)Otx(4)Pax2/5/8(3)
Pax3/7(2)Pax4/6(2)Phox(2)Pitx(3)Prop(1)Prrx(2)Rax(2)Rhox(3)Sebox(1)
Shox(2)Tprx(5)Uncx(1)Vsx(2)      
 
Loci in Tprx of Human back to top..
Symbol/LocusNameFamilyOrganismRegulator
TPRX1tetra-peptide repeat homeobox 1TprxHuman 
TPRX1P1tetra-peptide repeat homeobox 1 pseudogene 1TprxHuman 
TPRX1P2tetra-peptide repeat homeobox 1 pseudogene 2TprxHuman 
TPRX2Ptetra-peptide repeat homeobox 2 pseudogeneTprxHuman 
TPRXLtetra-peptide repeat homeobox-likeTprxHuman