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TALE Class
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Pbx Family
The Pbx gene family (within the TALE class) is equivalent to the PBC gene class of Bürglin and Mukherjee (2007). The gene family contains four human genes, one human pseudogene, one Drosophila gene (exd) and one amphioxus gene. The Exd/Pbx proteins are known co-factors of Hox proteins, sometimes associating with the pentapeptide motif N-terminal to the homeodomain of Hox proteins (Moens and Selleri 2006).

Reference(s):
Bürglin TR, Mukherjee K (2007) J Mol Evol 65:137-153.
Moens CB, Selleri L (2006) Devel Biol 291: 193-206.
 
Families List of Class TALE :
Irx(8)Meis(5)Mkx(1)Pbx(5)Pknox(2)Tgif(9)    
 
Loci in Pbx of Human back to top..
Symbol/LocusNameFamilyOrganismRegulator
PBX1pre-B-cell leukemia homeobox 1PbxHuman 
PBX2pre-B-cell leukemia homeobox 2PbxHuman 
PBX2P1pre-B-cell leukemia homeobox 2 pseudogene 1PbxHuman 
PBX3pre-B-cell leukemia homeobox 3PbxHuman 
PBX4pre-B-cell leukemia homeobox 4PbxHuman