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CUT Class
Families List  Genes List
Homeobox genes in the CUT class (named after the Drosophila gene cut) encode proteins with one or more ~75-amino acid CUT domains N-terminal to a 60-amino acid homeodomain. There are three families of CUT class genes in the human genome (Onecut, Cux, Satb); a fourth gene family (Cmp) is present in invertebrates but not vertebrates. Bürglin and Cassata have proposed that the Satb genes evolved from Cmp genes. There are seven CUT-class homeobox genes in the human genome and three pseudogenes (Holland et al. 2007); amphioxus has four CUT-class homeobox genes.

Bürglin TR, Cassata G (2002) Int J Dev Biol 2002, 46:115-123.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
Families List of Class CUT :
Loci in CUT of All back to top..
Cux2-lCux2 likeCuxZebrafish 
LOC100000073one cut domain family member 2-likeOnecutZebrafish 
LOC571757special AT-rich sequence binding protein 1-likeSatbZebrafish 
Onecut-lOnecut likeOnecutZebrafish 
onecut1one cut domain, family member 1OnecutZebrafish 
onecut3one cut homeobox 3OnecutZebrafish 
onecutlone cut domain, family member, likeOnecutZebrafish 
satb2SATB homeobox 2SatbZebrafish 
si:ch211-251d10.5Cux likeCuxZebrafish 
ceh-21C. Elegans Homeobox 21OnecutNematode 
ceh-38C. Elegans Homeobox 38OnecutNematode 
ceh-39C. Elegans Homeobox 39OnecutNematode 
ceh-44C. Elegans Homeobox 44CuxNematode 
ceh-48C. Elegans Homeobox 48OnecutNematode 
dve-1DVE (Defective proVEntriculus in Drosophila) homolog 1CmpNematode 
Cux1 CuxMousemmu-mir-122
Cux2 CuxMouse 
Onecut1 OnecutMouse 
Onecut2 OnecutMousemmu-mir-218
Onecut3 OnecutMouse 
Satb1 SatbMouse 
Satb2 SatbMouse 
CUX1cut-like homeobox 1CuxHuman 
CUX2cut-like homeobox 2CuxHuman 
CUX2P1cut-like homeobox 2 pseudogene 1CuxHuman 
CUX2P2cut-like homeobox 2 pseudogene 2CuxHuman 
ONECUT1one cut homeobox 1OnecutHuman 
ONECUT2one cut homeobox 2OnecutHuman 
ONECUT3one cut homeobox 3OnecutHuman 
SATB1special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)SatbHuman 
SATB1P1SATB homeobox 1 pesudogene 1SatbHuman 
SATB2SATB family member 2SatbHumanhsa-mir-31
DveDefective proventriculusCmpHoneybee 
dvedefective proventriculusCmpFruitfly 
cux1cut-like homeobox 1 CuxFrog 
cux2cut-like homeobox 2CuxFrog 
onecut1one cut homeobox 1OnecutFrog 
onecut1.2one cut homeobox 1, gene 2OnecutFrog 
onecut3one cut homeobox 3 OnecutFrog 
satb1SATB homeobox 1 SatbFrog 
satb2SATB homeobox 2 SatbFrog 
chr10.1Onecut likeOnecutChicken 
chrZ.1Onecut likeOnecutChicken 
CUX1cut-like homeobox 1CuxChicken 
CUX2cut-like homeobox 2CuxChicken 
SATB1SATB homeobox 1SatbChicken 
SATB2SATB homeobox 2SatbChicken 
DveDefective proventriculusCmpBeetle