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HNF Class
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Proteins encoded by HNF class genes (named after rat Hnf1) have a domain weakly similar to the POU domain located N-terminal to a highly atypical and extended homeodomain (up to 81 amino acids). There are three human HNF-class homeobox genes in the human genome, in two gene families; amphioxus has four genes in three gene families (Takatori et al. 2008).

Reference(s):
Bach I et al. (1991) Nucleic Acids Res 19:3553-3559.
Chen S et al. (2006) Genome Res 114:131-136.
Holland et al. (2007) BMC Biology 5:47.
Takatori N et al (2008) Dev Genes Evol 218: 579-590.
 
Families List of Class HNF :
Hmbox(1)         
 
Loci in HNF of Nematode back to top..
Symbol/LocusNameFamilyOrganismRegulator
hmbx-1HMBOX (mammalian HoMeoBOX gene) homologHmboxNematode