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LIM Class
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The LIM homeobox gene class includes proteins with LIM domains (zinc-finger-containing protein-protein interaction domains) and a homeodomain. There are other genes that encode LIM domains but not homeodomains; these are not included. The term LIM is derived from the nematode lin-11, mammalian Isl1 and nematode mec-3 genes. There are 12 LIM class homeobox genes in the human genome, in six gene families, and no pseudogenes. There are 7 LIM class homeobox genes in amphioxus (Takatori et al. 2008)

Reference(s):
Hobert O, Westphal H (2000) Trends in Genetics 16:75-83.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
Takatori N et al (2008) Dev Genes Evol 218: 579-590.
 
Families List of Class LIM :
Isl(2)Lhx1/5(2)Lhx2/9(2)Lhx3/4(2)Lhx6/8(2)Lmx(2)    
 
Loci in LIM of Mouse back to top..
Symbol/LocusNameFamilyOrganismRegulator
Isl1 IslMousemmu-mir-17
Isl2 IslMouse 
Lhx1 Lhx1/5Mouse 
Lhx2 Lhx2/9Mouse 
Lhx3 Lhx3/4Mouse 
Lhx4 Lhx3/4Mouse 
Lhx5 Lhx1/5Mouse 
Lhx6 Lhx6/8Mouse 
Lhx8 Lhx6/8Mouse 
Lhx9 Lhx2/9Mouse 
Lmx1a LmxMouse 
Lmx1b LmxMouse