Home | Human | Mouse | Chicken | Frog | Zebrafish | Amphioxus | Fruitfly | Beetle | Honeybee | Nematode
Total | HomeoReg | Summary | Download | Compare | BLAST | Search (gene symbol, e.g. HOX)

SINE Class
Families List  Genes List
Homeobox genes in the SINE class (named after the Drosophila gene sine oculis) encode proteins with a 115-amino acid 'SIX domain' and a 60-amino acid homeodomain. There are six human genes in three gene families. Amphioxus has one gene from each family.

Reference(s):
Kawakami K, Sato S, Ozaki H, Ikeda K (2000) BioEssays 22:616-626.
 
Families List of Class SINE :
Six1/2(18)Six3/6(17)Six4/5(13)       
 
Loci in SINE of All back to top..
Symbol/LocusNameFamilyOrganismRegulator
six1asine oculis homeobox homolog 1aSix1/2Zebrafish 
six1bsine oculis homeobox homolog 1bSix1/2Zebrafish 
six2asine oculis-related homeobox 2aSix1/2Zebrafish 
six2bsine oculis-related homeobox 2bSix1/2Zebrafish 
six3asine oculis homeobox homolog 3aSix3/6Zebrafish 
six3bsine oculis homeobox homolog 3bSix3/6Zebrafish 
six4.3sine oculis homeobox homolog 4.3Six4/5Zebrafish 
six4asine oculis homeobox homolog 4aSix4/5Zebrafish 
six4bsine oculis homeobox homolog 4bSix4/5Zebrafish 
six6asine oculis-related homeobox 6aSix3/6Zebrafish 
six6bsine oculis-related homeobox 6bSix3/6Zebrafish 
six7sine oculis homeobox homolog 7Six3/6Zebrafish 
six9sine oculis homeobox homolog 9Six1/2Zebrafish 
ceh-32C. Elegans Homeobox 32Six3/6Nematode 
ceh-33C. Elegans Homeobox 33Six1/2Nematode 
ceh-34C. Elegans Homeobox 34Six1/2Nematode 
unc-39UNCoordinated 39Six4/5Nematode 
Six1 Six1/2Mouse 
Six2 Six1/2Mouse 
Six3 Six3/6Mouse 
Six4 Six4/5Mouse 
Six5 Six4/5Mouse 
Six6 Six3/6Mouse 
SIX1SIX homeobox 1Six1/2Humanhsa-mir-185
SIX2SIX homeobox 2Six1/2Human 
SIX3SIX homeobox 3Six3/6Human 
SIX4SIX homeobox 4Six4/5Human 
SIX5SIX homeobox 5Six4/5Human 
SIX6SIX homeobox 6Six3/6Human 
OptixOptixSix3/6Honeybee 
Six4Six4Six4/5Honeybee 
SoSine oculisSix1/2Honeybee 
OptixOptixSix3/6Fruitfly 
Six4Six4Six4/5Fruitfly 
sosine oculisSix1/2Fruitfly 
six1SIX homeobox 1Six1/2Frog 
six2 SIX homeobox 2 Six1/2Frog 
six3 SIX homeobox 3 Six3/6Frog 
six3b Six3/6Frog 
six4 Six4/5Frog 
six6SIX homeobox 6Six3/6Frog 
SIX1SIX homeobox 1Six1/2Chicken 
OptixOptixSix3/6Beetle 
Six4Six4Six4/5Beetle 
SoSine oculisSix1/2Beetle 
Six1/2Six1/2Six1/2Amphioxus 
Six3/6Six3/6Six3/6Amphioxus 
Six4/5Six4/5Six4/5Amphioxus