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ZF Class
Families List  Genes List
Genes in the ZF (zinc finger) class encode proteins with zinc finger motifs in addition to one or more homeodomains. There are 14 members of the ZF homeobox gene class in the human genome (plus one pseudogene), which can be divided into five distinct gene families. There are many additional zinc finger-containing genes in the human genome that do not contain homeobox sequences; these are not included in the ZF homeobox gene class. As argued by Holland et al. (2007), it is logical to include the HOMEZ gene in the ZF class, even though it does not encode zinc fingers, because its homeodomain sequences are clearly related to those encoded by some of the ZF genes. Amphioxus has five ZF-class genes.

Reference(s):
Bayarsaihan D et al. (2003) , Proc Natl Acad Sci USA 100:10358-10363.
Holland PWH, Booth HAF, Bruford EA (2007) BMC Biology 5:47.
 
Families List of Class ZF :
Adnp(2)Tshz(2)Zeb(2)Zfhx(3)Zhx/Homez(5)     
 
Loci in ZF of Frog back to top..
Symbol/LocusNameFamilyOrganismRegulator
adnpactivity-dependent neuroprotector homeoboxAdnpFrog 
adnp2ADNP homeobox 2AdnpFrog 
homezhomeobox and leucine zipper encoding Zhx/HomezFrog 
tshz2teashirt zinc finger homeobox 2TshzFrog 
tshz3teashirt zinc finger homeobox 3 TshzFrog 
zeb1zinc finger E-box binding homeobox 1 ZebFrog 
zeb2zinc finger E-box binding homeobox 2 ZebFrog 
zfhx2zinc finger homeobox 2ZfhxFrog 
zfhx3zinc finger homeobox 3ZfhxFrog 
zfhx4zinc finger homeobox 4 ZfhxFrog 
zhx1zinc fingers and homeoboxes 1 Zhx/HomezFrog 
zhx2zinc fingers and homeoboxes 2Zhx/HomezFrog 
zhx2b Zhx/HomezFrog 
zhx3zinc fingers and homeoboxes 3Zhx/HomezFrog